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MRS work at 3 Tesla (3T) from one research group demonstrated elevated levels of ventricular lactate in cerebrospinal fluid (CSF) [14,15,16,17], as well as a reduction in the major endogenous free radical scavenger, glutathione (GSH) [16, 18]

However, given the small number of patients treated with 100 mg compared with 80 mg, no statistical comparison was possible between the 2 doses