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The impact of the intervention was determined by measuring the resulting erythrocyte and leucocyte glutathione concentrations, and biomarkers of oxidative stress

Moreover, the standard deviations for all enzymes after Bu treatment were higher in the control group compared to that seen in patients received prophylactic NAC treatment

A mouse model that utilized immunization with CEP to drive a DAMD pathology developed drusen and RPE lesions mimicking those seen in humans with DAMD, a phenotype not naturally observed in mice [181]