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What to Expect from Your B12 Injection The treatment process is simple and minimally invasive

Once injected, Sermorelin travels to the anterior pituitary gland and activates it

Symmetric basal ganglia change Serum lactate: Normal Muscle morphology: Normal Biochemistry: Complex I deficiency NDUFS4 Variant: Leigh syndrome Epidemiology Common autosomal recessive cause of complex I-associated Leigh Syndrome Genetics Inheritance: Recessive Clinical Characteristic Leigh presentation Course: Onset & demise typically 8 months of life: No later than 30 months Cardiomyopathy (33%): Hypertrophic Neuroradiology Bilateral symmetrical basal ganglia lesions: May extend to cerebral peduncles, pons and medulla Cerebral atrophy Lethal Infantile Mitochondrial Disease (MC1DN9) 46 : Complex I NADH Dehydrogenase (Ubiquinone) Fe-S Protein 6 (NDUFS6)

doi: 10.1152/ajpgi.00229.2016