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Disclosures: Nadeen Habboub: Nothing to Disclose, Despoina Chrysostomou: Nothing to Disclose, Benjamin Challis: Nothing to Disclose, Laura Martinez-Gili: Nothing to Disclose, Julian Marchesi: Nothing to Disclose, Marc Dumas: Nothing to Disclose, Mark Thursz: Durect: Consultant, GSK: Consultant, Resolution Tx: Consultant, Intercept: Consultant, Galecto: Consultant, Durect: Consultant, Benjamin Mullish: Nothing to Disclose, Pinelopi Manousou: Nothing to Disclose 1053 GROWTH HORMONE RESHAPES THE GUT MICROBIAL PROFILE IN INDIVIDUALS WITH METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE AFTER SIX MONTHS OF TREATMENT Elizabeth Jensen 1 Jonathan Young 2 Mark Chicote 3 Edward List 2 Kathleen Corey 4 John Kopchick 2 Darlene Berryman 2 Laura Dichtel 4 , 1 Cleveland Clinic Foundation

The 2026 study therefore proposes a context-dependent role in which BACH1 stabilization may promote the expression of selected angiogenesis-related genes under the tested endothelial and redox conditions