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157 Following disruption of the urothelial barrier by damage to tight junctions, the presence of these pathogenic bacteria may increase susceptibility to carcinogenic insults

Yudkin JS et al

By combining deuterium tracing and carbon labelling, this paper shows that in addition to the oxPPP, one-carbon metabolism also makes a significant contribution to the maintenance of NADPH

3.6 Increased host defense against bacterial infection Five GO:BP terms exhibited specific enrichment in proteins upregulated in CHL, including defense response to bacterium ( p adjusted = 6.8E-14) response to bacterium ( p adjusted = 2.4E-11), antimicrobial humoral response ( p adjusted = 2.1E-13), antibacterial humoral response ( p adjusted = 9.5E-10), and defense response to fungus ( p adjusted = 5.1E-10) (Supplementary Table S6)