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Injectable/IV NAD+ is not FDA-approved (or approved by any major regulator) for energy, metabolic or longevity uses, and its safety and efficacy for these uses are not established presented for research and educational use only

Probes were labeled with the VIC-reporter dye (ABI) for wild type and the FAM-reporter dye for the mutant, respectively

Most patients experience a staged response: improved energy and sleep within 1 week, reduced neuropathic pain by week 3-4, and enhanced cognitive function after 6-8 weeks

As pointed out by the authors, the study was limited to non-smokers and may have missed an effect in those whose lungs were compromised by smoking