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Table 4:Methylation of histones Phosphorylation Serine, threonine and tyrosine residues are phosphorylated in all of the core histone proteins and many variants, and are associated with many cellular processes including transcription regulation, DNA repair, mitosis and apoptosis

Based on the evidence provided by Evidence Development and Standards and its partners, the Ontario Health Technology Advisory Committeea standing advisory subcommittee of the Health Quality Ontario Boardmakes recommendations about the uptake, diffusion, distribution, or removal of health interventions to Ontarios Ministry of Health and Long-Term Care, clinicians, health system leaders, and policy-makers