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Decreased levels of carnosine seen in our study in both ME/CFS and long COVID may contribute to patients experience of muscle fatigue, which has been previously associated with acidosis [79]

Moreover, studies have identified BRD4, an epigenetic reader protein that recognizes and binds to acetylated histones, as a crucial contributor to the pathogenesis of PAH [113]

[] Instead, FIS1 is more critical at organelle contact sites, particularly in promoting mitochondrial fission during mitophagy via lysosomal recruitment