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The Acsl4 conditional knockout (cKO) model ( Acsl4 fl/fl Ksp Cre ) was engineered through crossbreeding of Acsl4 fl/fl mice with Ksp Cre transgenic strains, while the Fsp1 fl/fl Ksp Cre cKO mice were generated using analogous breeding strategies

Ling H, Spizzo R, Atlasi Y, Nicoloso M, Shimizu M, Redis RS, Nishida N, Gaf R, Song J, Guo Z, Ivan C, Barbarotto E, De Vries I, Zhang X, Ferracin M, Churchman M, van Galen JF, Beverloo BH, Shariati M, Haderk F, Estecio MR, Garcia-Manero G, Patijn GA, Gotley DC, Bhardwaj V, Shureiqi I, Sen S, Multani AS, Welsh J, Yamamoto K, Taniguchi I, Song MA, Gallinger S, Casey G, Thibodeau SN, Le Marchand L, Tiirikainen M, Mani SA, Zhang W, Davuluri RV, Mimori K, Mori M, Sieuwerts AM, Martens JW, Tomlinson I, Negrini M, Berindan-Neagoe I, Foekens JA, Hamilton SR, Lanza G, Kopetz S , Fodde R , Calin GA

Research involving GHK-Cu has examined interactions with signaling networks associated with extracellular matrix regulation, structural protein organization, metal-ion transport processes, and peptide-mediated cellular communication