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Description

Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5

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Due to the central role of glutamate in ALS, experimental therapies have been investigated and developed targeting glutamate signaling pathways or aimed at enhancing glutamate transport (EAAT2) function in order to restore glutamate homeostasis 34

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10.1002/bab.1797 22 QiaoD.ZhangZ.ZhangY.ChenQ.ChenY.TangY.et al (2021)

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1 Introduction The lens contains high levels of the antioxidant glutathione (GSH) which exceed levels found in other ocular tissues (1, 2)

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