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Similarly, ZIP10 is regarded as a cancer marker based on its methylation in CRC

van der Steen, W., den Heijer, T., Groen, J

Furthermore, excessive intake can lead to specific toxicities, such as the potential for liver damage from high-dose green tea catechins or gastrointestinal distress from concentrated capsaicin 52,53

It sits at the intersection of metabolic and longevity research, studied for how mitochondrial-derived signals influence cellular energy homeostasis and the metabolic shifts associated with aging