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These injectable biomaterials could potentially replace the nucleus pulposus while promoting surrounding tissue repair

This "paradoxical response" (where treatment temporarily makes symptoms worse) includes: Numbness and tingling Shooting pains Joint pain Increased sensitivity Temporary inflammation (swelling and irritation) While these symptoms generally indicate that treatment is working (as nerves begin to repair themselves), they can be distressing for patients and may require additional treatment for comfort

A detailed review of studies is key to understand its impact on B12 absorption

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