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This result not only enables us to determine how the CAR-HSC complex properly performs SC exfoliation after penetration in SC layers, but also implies that NMR can be a powerful tool for investigating interactions between molecules

As a mitigation strategy, if the test for period effect post unblinding was significant, then the statistical model for the primary outcome had to be recomputed only on the data from the first period of the trial (where period effect is taken out)as recommended by clinical practice (3537)

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