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Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation

(2021) speculated that the downregulated genes involved to amino acid synthesis pathways could be due to the presence of high levels of NaCl

P53 inhibits cystine uptake and sensitizes cells to ferroptosis by inhibiting the expression of SLC7A11, a key component of cystine/glutamate retrotransporters