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Using DNA methylation data of postmortem DLPFC brain from 468 individuals [20], we found CpG sites scattered around CYP2D6 are significantly interacted with both functional SNPs (e.g., rs133377) and chromatin (e.g., peak16933) (Table S8), implying they function together to regulate CYP2D6 gene transcription

As a small-molecule tripeptide involved in redox regulation, glutathione is most commonly utilized in in vitro systems and biochemical assays , with additional applications in controlled in vivo research models