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In instances of colorectal adenocarcinoma (CAC), alterations affecting the Wnt/-catenin signaling pathway manifest exclusively during advanced disease stages, subsequent to the occurrence of mutations in the TP53 and K-Ras genes (Intarajak et al., 2019)

doi: 10.3389/fendo.2024.1429884

explored the neuroprotective potential of an aqueous extract of Solanum nigrum (AESN) in preventing retinal ganglion cell (RGC) degeneration using a carbomer-induced glaucoma rat model