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One possibility is that Cu may play role in inflammatory responses involved in atherosclerosis

Determination of serum biochemical parameters Serum BUN (mg/dl), creatinine(mg/dl), uric acid(mg/dl), Ca (mg/dl), P(mg/dl) and total protein (g/dl) were measured at the end of the study by an enzymatic colorimetric assays with a DIRUI (CS-T240, China) auto-clinical chemistry-analyzer and commercial diagnostic kit Biosystem company, Spain

Of course there are other sources of acid formation for both plants and meats such as amino acids, other fatty acids, uric acid, etc

Twenty women with refractory IC/BPS symptoms were treated with 30-min session of PTNS weekly for 12 consecutive weeks