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A recent study concludes: Increasing glutathione remains a promising therapeutic strategy to slow or prevent MCI and Alzheimers disease. Considering that glutathione levels continue to decline with age, and both AD and MCI increase with age, intervention with effective glutathione can play an important role in slowing or preventing the progression of these diseases

Additionally, PD caused histological damage indicative of apoptosis and downregulated of the PI3K/Akt signaling pathway, indicating continuing apoptosis

The following section describes the interplay of oxidative stress, neuroinflammation, and intraocular pressure before presenting the three neuroprotective strategies to support the optic nerve