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and, we can also deploy fragment-based generative models to apply generative chemistry to de novo design new scaffolds based upon the known caudatin pharmacophores and bioactive fragments ( Statements Author contributions GS: Data curation, Investigation, Writing original draft

Chinese hamster ovary cells, stably expressing the myc-vector (CHO), or N -terminal myc-tagged, WT human parkin (CHO-parkin) were also used [26]

In normal cells , it helps by promoting telomerase activity, while in cancer cells , other pathways contribute

An increased relative risk of death in NSAID users continued during the follow-up period of 4 years