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Martha M

In a phase III randomized-controlled trial, Chinese patients with advanced GEA failing two or more prior lines of chemotherapy, were assigned to apatinib 850 mg once daily or placebo ( Table 1 )

[36] This degradation process releases the drug payload specifically into cancerous or tumorous tissue, leveraging the significant difference in redox potential between the oxidizing extracellular environment and the reducing intracellular cytosol