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The concept of the ROSImmune Mismatch is critical because it moves beyond the general observation of oxidative stress to define the specific, differential selection pressure that favors tumor survival and immunosuppressive cells over anti-tumor effector cells

A., Grant, C

Power analysis and advanced statistics can potentially help to reduce the number of replicates ( While pseudo-replication due to the re-use of animals can be compensated for using Bayesian statistics ( Pagurus bernhardus ( The number of replicates should then be carefully decided based on such previous experiments with the chosen model organisms

Tsimikas, S