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Conclusion: Elevated systemic IgM titers recognizing MDA facilitates complement recruitment which enhances cell death, thereby promoting alcohol-associated liver disease

Consistent with this, according to the histological staining of the tumor sections, a loose cell arrangement with the lowest expression of GLUT1, p65, and Ki67 was observed in the T-AsiG-CPL group, confirming the dual inhibition of ECM and tumor cell energy metabolism (Fig