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In florid reactions, areas of necrosis include degenerating neutrophils admixed with the necrotic hepatic parenchymal cells

Procyanidins, potent free radical scavengers derived from grape seeds, reduce iron content and thiobarbituric acid-reactive substances (TBARS), inhibit ACSL4 and ALOX15 expression, and enhance HO-1, Nrf2, GSH, and GPX4 levels, ultimately improving motor function in SCI mice (242)