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Ring stage enrichment with Streptolysin O Enriched ring-stage cultures were generated with Streptolysin O (SLO) as previously described with modifications 29

Suddenly cutting that fuel supply triggers an adaptive response that conserves energy wherever possible

These mechanisms collectively trigger and sustain inflammation, atherosclerosis, and organ-specific complications such as retinopathy, nephropathy, neuropathy, metabolic-dysfunction associated steatotic liver disease (MASLD), cardiopathy, and brain disease [5]

CP is a cylinder-shaped structure with two outer rings () and two inner rings (), which has four heptameric rings with seven or seven subunits[12]