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Several studies have proved the clinical efficacy of Doxil, where improved tumor response rates and a favorable safety profile were observed compared to the conventional formulation of doxorubicin

10.3389/fphar.2014.00097 222 PiacentiniR.Li PumaD

Dimethyl fumarate (DMF) and its metabolite monomethyl fumarate (MMF) modulate some signaling proteins activity and intracellular concentration, such as the nuclear factor (erythroid-derived 2)-like 2 (Nrf2), nuclear factor-kappa B (Nf-B), and cyclic adenosine monophosphate