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In the aspect of autophagy and the Nrf2-Keap1 antioxidant pathway, SQSTM1, TFEB, Sestrin2, and TRIM16 are all involved in different conditions and act as the scaffolds connecting the two pathways (Table 1)

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ORL1, a novel member of the opioid receptor family

Cells 11, 2529

Finally, a meta-analysis by Peart and investigators [500] involving sodium bicarbonate reported the overall treatment effect to be moderate at improving performance with nearly all measured ergogenic outcomes being influenced by the training status of the participants