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Whether liver-specific GSH synthesis was responsible for downregulated lipogenic gene expression and reduced serum triglycerides or whether these phenotypes were a byproduct of a liver-independent process in Gclc KO mice was unclear

Although less studied, SCFAs also affect CD8 + T cells, which are essential for intracellular pathogen clearance and tumor surveillance

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The integrity of the BBB model was tested by permeability assays for SF and albumin marker molecules