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This work received support from the National Natural Science Foundation of China (82374321), the Tianjin-Hebei-Beijing Key Industry Chain Achievement Transformation Project (246Z2403G), and the Jie-Bang-Gua-Shuai Project of the Beijing University of Chinese Medicine (2023-JYB-JBZD-035)

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The response regulator DevR , which controls mycobacterias hypoxic responses, is absent in a mutant that cannot tolerate larger phage bursts or undergo synchronized growth in response to VC pre-exposure