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intracellular GSSG: *p = 0.0105 (sgNTC vs

In GT-3a, the most difficult to treat genotype, RZR is 6 times more potent than velpatasvir, and retains sub-nM potency against NS5A RAVs (such as A30K, Y93H) which were treatment-emergent in HCV GT3 patients failing DAAs (Figure 1C)