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Whole animal studies have strengths in that the experimental system contains the variety of interactions seen in the body

During the progression of cirrhosis, alterations occur in the morphology and dimensions of the liver, with the liver volume remaining stable or exhibiting a relatively increase in early stages, followed by a reduction in volume during advanced stages, and a gradual decline in the liver's reserve function

Gheorghe G, Ilie M, Bungau S, Stoian AMP, Bacalbasa N, Diaconu CC (2021) Is there a relationship between COVID-19 and hyponatremia

Chiche L, Forel JM, Thomas G, Farnarier C, Vely F, Blery M, et al