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Indeed, several studies have reported that immunosuppression induced by exercise excess can increase the risk of infections and the development or aggravation of overtraining syndrome (Reference Gleeson, Pyne and Elkington76,Reference Edouard, Junge and Sorg77)

The study on MSN-based chemotherapeutic combination medicines is still in its infancy, but as our knowledge of materials and illnesses grows, so are the potential MSN-based DDS applications