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Existing clinical studies often suffer from single-center experiments, small sample sizes, short follow-up durations, and the absence of standardized endpoint measures, which challenge comparative analyses across studies and the establishment of conclusive evidence

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This occurs when the skin produces less melanin after healing

T14 plays a trophic role in early development through the calcium signaling of 7-nAChR, but the tolerance of neurons to calcium ion flux significantly decreases in the elderly (Graur et al., 2023)