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The initial results of the ENCODE project (Encyclopedia of DNA Elements) indicate that 80% of the genome contains elements linked to biochemical functions filled with enhancers (regulatory DNA elements), promoters (the sites at which DNA transcription into RNA is initiated) and numerous previously overlooked regions that encode RNA transcripts that are not translated into proteins, but that might have regulatory roles

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[PubMed] [Google Scholar] 25.Barassi A., Corsi Romanelli M.M., Pezzilli R

The review yielded an evidence base of 303 articles after application of inclusion/exclusion criteria