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Boxes represent the interquartile range (IQR) and whiskers extend to 1.5 the IQR or to the minimum and maximum values if no point exceeds that range

A 2.5 mg track has short direct data and real-world support for stable maintainers, but continuing tirzepatide has much stronger evidence than stopping. At week 112, stepping down to 5 mg preserved 16.6% weight loss versus 21.9% on the top dose and 9.9% on placebo

The primary concern for the FDA was the lack of large-scale, randomized controlled trials, which are the gold standard for new drug approval

Relevant Experience: Canadian Gas Utility - Engagement lead for development of economic lifecycle models for 33 asset classes U.S