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In this study, we combine transcriptional profiling with time-of-flight mass cytometry (CyTOF) to systematically analyze the functional characteristics and immune receptor repertoire of NK cells in individuals at different status of Mtb infection, with an aim to identify the critical NK checkpoint molecules and their signaling network that may serve as new targets for improving host anti-Mtb immunity

Table 1 Clinical and preclinical studies reporting the effect of the KD on SUD

Crystallization of Pt GSTF8 in presence of ()-catechin and GSH Purified Pt GSTF8 in 30 mM Tris, pH 8, 200 mM NaCl, 1 mM EDTA was concentrated to 12.4 mg ml 1 using an Amicon Ultra-4 device (10 kDa cut-off) (Merck Millipore) and supplemented with 1 mM GSH and 25 mM ()-catechin immediately before crystallization

Different research protocols can use very different amounts of the same 80 mg vial