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Description

Apremilast, a phosphodiesterase 4 inhibitor, offers a safer hepatic profile but has lower efficacy than traditional systemic agents

Furthermore, GCH1 (GTP cyclohydrolase 1), which is the rate-limiting enzyme for synthesizing tetrahydrobiopterin (BH4), inhibits ferroptosis through GPX4-independent mechanisms

It is a compounded medication made by specialized pharmacies, so you can only obtain it legally with a doctors prescription through a 503A compounding pharmacy