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It is not clear how glutathione is transported across the ER membrane, but cells involved in intensive secretion are also known to secrete GSSG

doi: 10.1016/j.nbd.2006.12.019 104

The interactive nature of traditional formulations is exemplified by curcumin, whose bioavailability is markedly increased when co-administered with piperine, an alkaloid from black pepper ( Piper nigrum ), demonstrating how phytochemical interactions can enhance therapeutic efficacy [31]