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However, despite molecular evidence of oxidative damage, antioxidant therapies remain underutilized in the clinical management of obesity-related endometrial disorders

Although Chac2 has also been proposed to function as a GSH-degrading enzyme based on its approximately 50% sequence similarity to Chac1 , it shows about 20-fold lower catalytic efficiency than Chac1 on GSH degradation (20)

In vivo studies have shown that R162 prevents lung cancer metastasis in patient-derived xenograft models (Jin et al., 2018)

Its sequence comes from a small fragment of a larger protein found in human gastric juice, the digestive fluid produced by the stomach