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By reducing inflammation MSM helps to reduce pain and improve the mobility

These limitations have contributed to the lack of conclusive clinical efficacy observed to date (Kurkinen, 2023)

Exclusions occurred solely due to technical failure or sample loss during tissue processing, and no animals were excluded based on experimental outcomes

This modulation ultimately leads to a suppression of the production and secretion of inflammatory cytokines, including TNF-, IL-1, and IL-6, thereby regulating inflammatory reactions and mitigating tissue damage in T cell-mediated autoimmune diseases, such as RA, MS, and inflammatory bowel disease (218)