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Elsevier, pp

Additionally, granulosa cells in women with endometriosis exhibit apoptosis, mitochondrial dysfunction, disrupted steroid hormone production, and increased inflammatory markers, further compromising follicle health ( These changes contribute to significant oocyte quality defects

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R4VPL3-1 induces ferroptosis in cancer cells To identify the cellular pathways involved in R4VPL3-1-induced cell death, we performed transcriptional analysis using whole transcriptomic sequencing and compared A375R cells treated for two hours with 10 M VHL-r or 10 M R4VPL3-1 (Fig