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CD44 has been studied in cancer due to the involvement of its splice variants in tumor progression (67)

found that ASCT2 ligands chloroalanine, aminooxetane-3-carboxylate (AOC), and -FBP also inhibit ASCT2-mediated glutamine uptake in human melanoma cells [104]

The MTHFR enzyme creates the methylfolate

Validating the action of SP and MH in preventing ROT-induced cell damage and preserving neuronal cell morphology We then tested the potential effects of SP and MH on the survival and morphology of cells in primary neuron culture