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Folate and DNA methylation: a review of molecular mechanisms and the evidence for folate's role

(Lond.) 9 , 36 (2012)

Mutations in genes such as SNCA, LRRK2, PARK7, PINK1, and VPS35 are associated with familial forms of PD, while pesticide exposure, heavy metals, and industrial chemicals contribute to sporadic cases

336 While cell-based display methods typically create the genotype to phenotype linkage through compartmentalization, CFE-based selection methods, like ribosome 337 and mRNA 338 display, frequently leverage a direct physical link between a displayed protein and its transcript to maintain the genotype and phenotype linkage