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This indicates that KO has great potential as a skin protectant

Biochem J 342(1):111117 Wu Q, Huang K, Xu H (2003) Effects of long-term selenium deficiency on glutathione peroxidase and thioredoxin reductase activities and expressions in rat aorta

doi: 10.1136/gutjnl-2022-326928

The reference nutrient intake (RNI) for adults in the UK is 1.5 micrograms daily, though therapeutic doses for treating deficiency are substantially higher