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Certain single nucleotide polymorphisms (SNPs), or variants of this gene, result in the reduced capacity of this enzyme ( 2 )

Nonetheless, the therapeutic potential of glycine as a novel treatment for MASLD is supported by recent preclinical studies that demonstrated the ability of glycine-based supplements to reduce hepatic fat, inflammation, and fibrosis in rodents and non-human primates with MASLD 31,32

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