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All subjects from cohorts 1 through 3, and 1 subject from cohort 4 were evaluated at a variety of time points

doi: 10.1002/ctm2.v12.5 32 Ketelut-CarneiroNFitzgeraldKA

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The enzyme 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR) attaches a methyl group from methylcobalamin (b12) to homocysteine resulting in methionine