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However, the real effects of L-carnitine supplementation, taking into account its above-mentioned positive and possibly negative properties ( via TMAO), on the process of atherosclerosis and atheroma plaque merit further investigations

Moreover, how oxidative stress and ERS jointly influence specific signaling pathways, such as NF-B, MAPK, SIRT1, and how they affect the balance between autophagy and apoptosis, remains an important question to address

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AK Voss: conceptualisation, resources, formal analysis, supervision, funding acquisition, investigation, visualisation, methodology, project administration, and writingoriginal draft, review, and editing