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To explore humoral factors that regulate EBC-1 supernatant-induced tube formation independently of VEGF-A, we analysed proteins in the supernatant by using mass spectrometry (MS) and identified 1,007 proteins (Table SIII), most related to adhesion, cytoskeletal and nuclear proteins, indicating that there were microvesicles such as exosomes in the EBC-1 supernatant (10,11)

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Additionally, increased frequencies of diabetes mellitus, high blood pressure, kidney pathologies, coronary artery disease and raised serum lipids were identified [20]

Biomedicines 10 (2), 330