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In vivo investigations revealed that ultrasound-activated TiO-based SDT causes ICD, facilitates the release of DAMPs, and augments T-cell infiltration into the TME

However, the biocompatibility and biosafety of nanostructures are an issue and therefore, their clinical application requires highlighting their long-term safety

Role of the NADPH oxidases DUOX and NOX4 in thyroid oxidative stress

8 Therapeutic approaches targeting macrophage-ferroptosis interactions Macrophages enhance the efficacy of anti-tumor treatments by remodeling the tumor microenvironment