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A groundbreaking study in Nature Medicine (s41591-025-03944-9) is fundamentally shifting our understanding of prediabetes

Switzerland) 8(9) Lotinun S, Ishihara Y, Nagano K, Kiviranta R, Carpentier VT, Neff L, Parkman V, Ide N, Hu D, Dann P, Brooks D, Bouxsein ML, Wysolmerski J, Gori F, Baron R (2019) Cathepsin K-deficient osteocytes prevent lactation-induced bone loss and parathyroid hormone suppression

OXPHOS activity analysis in skeletal muscle showed typical features of Fe/S-cluster deficiency with decreased activities of complexes I, II, and III, and a decreased activity of the Fe/S-cluster matrix enzyme aconitase [34]

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