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Downregulation of the cell cycle pathway and the Notch signaling pathway, likely induced by Foxg1 knockdown in supporting cells, has been shown to lead to the generation of new hair cells (Zhang et al., 2020)

It can transactivate ferritin in response to ferroptosis triggers and inflammation, and by regulating p21, it can bolster the antioxidative defenses of the brain, particularly by inhibiting glutathione degradation and enhancing GPX4 activity [67]

gingivalis , synergistically drives ferroptosis in periodontal cells through multidimensional virulence factors, including lipopolysaccharide, gingipains, and the metabolic end product butyrate (46)

S -Based nucleophilicity The conjugate base of thiols are potent nucleophiles